| Acamprosate Calcium is avaliable in form of Tablets, | | | | Calcium with care and monitor renal function. |
| delayed-release 333 mg. acamprosate calcium (equiv. | | | | * Reduce dose in patients with moderate renal |
| to 300 mg acamprosate). | | | | impairment. Do not administer to patients with severe |
| Dosage Instructions for Acamprosate Calcium Drug | | | | renal impairment. |
| Adults: PO Two 333 mg tablets tid. | | | | * The safety and efficay of Acamprosate Calcium |
| Renal Impairment Adults: PO Start with 333 mg tid in | | | | medicine have not been studied in children and |
| patients with moderate renal impairment (Ccr 30 to 50 | | | | adolescents. |
| mL/min). Do not administer to patients with severe | | | | * Alcohol withdrawal symptoms are not eliminated or |
| renal impairment (Ccr 30 mL/min or less). | | | | diminished by acamprosate administration. |
| Contraindications of Acamprosate Calcium | | | | * Ensure that patient is participating in a comprehensive |
| Severe renal impairment (Ccr 30 mL/min or less); | | | | management program that includes psychosocial |
| hypersensitivity to any component of product. | | | | support. |
| Interactions of Acamprosate Calcium with other drugs | | | | * Monitor patient for depression or suicidal tendencies |
| Antidepressants: Weight gain and loss reported more | | | | often associated with alcohol dependence. Immediately |
| frequently compared with either agent alone. | | | | inform health care provider if depression or suicidal |
| Naltrexone: Acamprosate levels may be increased; | | | | behaviors or thoughts are noted. |
| however, no dosage adjustment is recommended. | | | | * Advise patient to continue acamprosate therapy as |
| What are the Side Effects of Acamprosate Calcium - | | | | directed, even in the event of a relapse. Instruct patient |
| Like other medicines, Acamprosate Calcium can cause | | | | to discuss any renewed drinking with health care |
| side effects. Some of the more common side effects | | | | provider. |
| of Acamprosate Calcium includ | | | | * Advise women to inform health care provider if |
| * Palpitation, syncope | | | | pregnant, planning to become pregnant, or |
| * Insomnia (7%); | | | | breastfeeding while taking Acamprosate Calcium. |
| * asthenia, anxiety (6%); | | | | What if Overdose of Acamprosate Calcium ? |
| * depression (5%); dizziness (3%); | | | | If you think you or anyone else taken overdose of |
| * dry mouth, | | | | Acamprosate Calcium , immediately telephone your |
| * paresthesia (2%); | | | | doctor or contact your local or regional Poisons |
| * headache, | | | | Information Centre Seek medical attention immediately. |
| * somnolence, | | | | You may need urgent medical attention. Diarrhea may |
| * decreased libido, | | | | be a sign of overdose of Acamprosate Calcium. |
| * amnesia, | | | | What if Missed Dose of Acamprosate Calcium ? |
| * abnormal thinking, | | | | If you miss a dose of Acamprosate Calcium medicine |
| * tremor, | | | | and you remember within an hour or so, take the dose |
| * vasodilatation, | | | | immediately. If you do not remember until later, skip the |
| * hypertension (at least 1%). | | | | dose you missed and go back to your regular |
| * ruritus (4%); | | | | schedule. Do not double doses. |
| * sweating (2%); | | | | Storage Conditions for Acamprosate Calcium : |
| * rash (at least 1%). | | | | Administer prescribed dose without regard to meals |
| Warnings and precautions before taking Acamprosate | | | | but administer with food if GI upset occurs or if |
| Calcium : | | | | administration with food increases compliance. Store |
| * Elderly: Because elderly are more likely to have | | | | Acamprosate Calcium tablets at controlled room |
| decreased renal function, select dose of Acamprosate | | | | temperature (59° to 86°F). |