| Pioneering medical research is going on at the | | | | cannot squeeze so hard, and so reduces the need to |
| University of Leicester into the use of Botulinum toxin - | | | | pass water frequently or suddenly. It may also reduce |
| commonly thought of as a beauty treatment | | | | the sensation of having a full bladder. Dr Douglas |
| – for bladder problems. | | | | Tincello commented: |
| Dr Douglas Tincello, Senior Lecturer at the University's | | | | "Overactive bladder is very difficult to treat well. Lots |
| Department of Cancer Studies and Molecular Medicine | | | | of our patients try different tablets and pelvic floor |
| and Consultant Gynaecologist at the Leicester General | | | | exercises but at least a third of them will not be better. |
| Hospital, is carrying out a randomised trial involving | | | | At the moment the only alternatives are to put up with |
| injecting botulinum toxin into the bladders of women | | | | it, or consider a very big operation which often means |
| who have overactive bladder disease. | | | | the patient ends up with a stoma bag. |
| The trial, which has received a grant of L158,000 from | | | | "Many patients just suffer in silence, but the quality of |
| the Moulton Charitable Trust, involves women whose | | | | life when you live with overactive bladder is similar to |
| conditions have not improved after tablet treatment. | | | | that of a patient on kidney dialysis. |
| Overactive bladder is a condition in which the bladder | | | | "Botulinum toxin has been tested already in spinal cord |
| tries to empty itself, rather than the patient retaining | | | | injury patients.This study is important to ascertain if it is |
| control. Symptoms include having to pass water very | | | | safe and effective in patients with overactive bladder. |
| often day and night, not being able to put off the need | | | | Botulinum toxin is a very exciting development and in |
| to do so, sudden urgency to pass water and | | | | the future may provide a simple and effective way to |
| sometimes incontinence. | | | | improve the quality of life in our patients." |
| The botulinum toxin relaxes the bladder muscle so it | | | | |